靶标 CNTNAP2 别名 CDFE; NRXN4; AUTS15; CASPR2; PTHSL1 宿主 Rabbit 稀释比例 WB 1:200-1000. IHC 1:20-100 Gene ID 26047 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9UHC6 蛋白分子量 148 kDa 储存液 pH7.4 PBS, 0.05% NaN3, 40% Glycerol 亚细胞定位 Cell membrane 免疫原 Fusion protein of human CNTNAP2 亚型 IgG 纯化方法 Antigen affinity purification 背景资料 This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation. 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB ELISA IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。