靶标 CNOT2 别名 CCR4 associated factor 2; CCR4 NOT transcription complex subunit 2; CCR4-associated factor 2; CCR4-NOT transcription complex subunit 2; CDC36; CNOT2; CNOT2_HUMAN; HSPC131; MSTP046; Negative regulator of transcription 2; NOT2 (negative regulator of transcription 2 yeast) homolog; NOT2; NOT2H; 宿主 Rabbit 稀释比例 WB 1:1000-3000. IHC 1:50-200. Gene ID 4848 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9NZN8 蛋白分子量 22/41/52/54/60kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 A synthetic peptide of human CNOT2 亚型 IgG 纯化方法 Affinity purification 背景资料 Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of embryonic stem (ES) cell identity. Public Immunogen Range 380-430/540 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。