靶标 EPHB4 别名 Ephb4; EPHB4_HUMAN; Ephrin receptor EphB4; Ephrin type-B receptor 4; Hepatoma Transmembrane Kinase; HTK; MYK 1; MYK1; TYRO 11; TYRO11; Tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase TYRO11; 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 2050 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P54760 蛋白分子量 33/45/56/108kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cell membrane Cytoplasm 免疫原 A synthetic peptide of human EPHB4 亚型 IgG 纯化方法 Affinity purification 背景资料 Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. Public Immunogen Range 880-930/987 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。