Solarbio K110332P Anti-IDH1 Polyclonal Antibody
- 销售价:
- ¥768.00
- 市场价:
-
¥960.00 - 编号:
- 202303101035724
- 货号:
- K110332P-50ul
-
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商品介绍
英文名称
Anti-IDH1 Polyclonal Antibody
靶标
IFT57
别名
IDH1;HEL-216;HEL-S-26;IDCD;IDH;IDP;IDPC;PICD
宿主
Rabbit
稀释比例
IHC 1:50-200.
Gene ID
3417
保存
Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot
O75874
蛋白分子量
47kDa
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位
Cytoplasm Nucleus
免疫原
A synthetic peptide of IDH1
亚型
IgG
纯化方法
Affinity purification
背景资料
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Public Immunogen Range
350-400/414aa
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
IHC
规格
50ul 100ul
使用前请离心。如有问题请及时联系我们。
商品参数
商品介绍 | |
---|---|
单位 | 支 |
品牌 | Solarbio |
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