靶标 LRRC19 宿主 Rabbit 稀释比例 WB 1:500-2000. IHC 1:25-100 Gene ID 64922 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9H756 蛋白分子量 42 kDa 储存液 pH7.4 PBS, 0.05% NaN3, 40% Glycerol 亚细胞定位 Cytoplasm Nucleus 免疫原 Fusion protein of human LRRC19 亚型 IgG 纯化方法 Antigen affinity purification 背景资料 LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530. 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 WB ELISA IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。