靶标 CD46 别名 AHUS2; Antigen defined by monoclonal antibody TRA 2 10; Antigen identified by monoclonal antibody TRA 2 10; CD46; CD46 antigen; CD46 antigen complement regulatory protein; CD46 molecule; CD46 molecule complement regulatory protein; Complement membrane cofactor protein; MCP; MCP_HUMAN; Measles virus receptor; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); Membrane cofactor protein; MGC26544; MIC10; TLX; TRA2.10; Trophoblast leucocyte common antigen; Trophoblast leukocyte common antigen; Trophoblast lymphocyte cross reactive antigen; 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 4179 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P15529 蛋白分子量 37/39/40/41/42/43/44kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cell membrane 免疫原 A synthetic peptide of human CD46 亚型 IgG 纯化方法 Affinity purification 背景资料 The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. Public Immunogen Range 35-85/392 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Chimpanzee Chlorocebus aethiops Cavia porcellus 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。