英文名称 Anti-EMR1 Polyclonal Antibody 靶标 靶标 别名 ADGRE1, Adhesion G protein-coupled receptor E1, EGF like module receptor 1, EMR1, EMR1 hormone receptor, F4/80, TM7LN3 稀释比例 WB 1:500-2000. IHC 1:400-1600. IF 1:50-500. Gene ID 2015 Swiss Prot Q14246 保存 Store at -20℃. Avoid freeze / thaw cycles. 蛋白分子量 90kDa 储存液 PBS with 0.02% sodium azide and 50% glycerol pH 7.3. 亚细胞定位 Cell membrane Multi-pass membrane protein 免疫原 Recombinant fusion protein of Human EMR1 亚型 IgG 纯化方法 Affinity purification 背景资料 EMR1 (EGF-like module containing mucin-like hormone receptor 1), also known as Adhesion G protein-coupled receptor E1 (ADGRE1), is a surface receptor with seven transmembrane segments that belongs to the EGF-7-transmembrane family of G protein-coupled receptors (PMID: 14647991, 7601460). EMR1 expression is restricted to eosinophilic granulocytes, where expression is overlapping with the eotaxin receptor CCR3 and the immunoglobulin-like lectin Siglec-8. Absence on other leukocytes, including basophils, implies that EMR1 is a highly specific marker for eosinophils in humans and may be used as a novel therapeutic target for eosinophilic disorders(PMID: 17823986, 24530099). F4/80, the murine homolog of EMR1, is a marker of murine macrophage. The apparent molecular weigh of F4/80 is 160 kDa, which is lager than the calculated molecular weight due to post-translational modifications (PMID: 7308288; 8647179). 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 WB ELISA IHC IF 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。