英文名称 Anti-IFIT1 Polyclonal Antibody 靶标 PLIN2 别名 C56;G10P1;IFI-56;IFI-56K;IFI56;IFIT-1;IFNAI1;ISG56;P56;RNM561 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 3434 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P09914 蛋白分子量 52/55kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 Recombinant protein of human IFIT1 亚型 IgG 纯化方法 Affinity purification 背景资料 Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses. Public Immunogen Range 1-350aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。