靶标 ATP6V1C1 别名 VATC; Vma5; ATP6C; ATP6D 宿主 Rabbit 稀释比例 WB 1:500-2000. IHC 1:100-200 Gene ID 528 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P21283 蛋白分子量 44 kDa 储存液 pH7.4 PBS, 0.05% NaN3, 40% Glycerol 亚细胞定位 Cytoplasm 免疫原 Fusion protein of human ATP6V1C1 亚型 IgG 纯化方法 Antigen affinity purification 背景资料 This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB ELISA IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。