靶标 STX5 别名 SED5; STX5A 宿主 Rabbit 稀释比例 WB 1:500-2000. IHC 1:50-200 Gene ID 6811 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q13190 蛋白分子量 40 kDa 储存液 pH7.4 PBS, 0.05% NaN3, 40% Glycerol 亚细胞定位 Cytoplasm 免疫原 Fusion protein of human STX5 亚型 IgG 纯化方法 Antigen affinity purification 背景资料 The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa (long) protein localized to the Golgi complex and endoplasmic reticulum, and a “short” 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes. 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB ELISA IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。