靶标 LFNG 别名 SCDO3 宿主 Rabbit 稀释比例 WB 1:500-2000. IHC 1:50-200 Gene ID 3955 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q8NES3 蛋白分子量 42 kDa 储存液 pH7.4 PBS, 0.05% NaN3, 40% Glycerol 亚细胞定位 Cytoplasm 免疫原 Fusion protein of human LFNG 亚型 IgG 纯化方法 Antigen affinity purification 背景资料 This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB ELISA IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。