靶标 BLOC1S2 别名 BLOS2;BORCS2;CEAP;CEAP11 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 282991 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q6QNY1 蛋白分子量 11/16kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 Recombinant protein of human BLOC1S2 亚型 IgG 纯化方法 Affinity purification 背景资料 Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes (PubMed:15102850, PubMed:17182842). In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (By similarity). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May play a role in cell proliferation (PubMed:15381421). Public Immunogen Range 1-99aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 IHC 规格 50ul 100ul 温馨提示： 使用前请离心。如有问题请及时联系我们。 Quick spin before use. If you have any questions, please contact us.