靶标 WDR41 别名 一抗 抗体 宿主 Rabbit 稀释比例 WB 1:1000-3000. IHC 1:50-200. Gene ID 55255 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9HAD4 蛋白分子量 46/52kDa 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 Recombinant protein of human WDR41 亚型 IgG 纯化方法 Affinity purification 背景资料 Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. Public Immunogen Range 1-350aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。