英文名称 Anti-APLP2 Polyclonal Antibody 靶标 APLP2 别名 APLP2;APLP-2;APPH;APPL2;CDEBP 宿主 Rabbit 稀释比例 WB 1:1000-3000. IHC 1:50-200. Gene ID 334 Swiss Prot Q06481 保存 Store at -20°C. Avoid freeze / thaw cycles. 蛋白分子量 59/79/81/85/87kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Secreted Nucleus 免疫原 A synthetic peptide of human APLP2 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. Public Immunogen Range 713-763/763 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。