英文名称 Anti-MCM7 Polyclonal Antibody 靶标 MCM7 别名 CDC47;MCM2;P1.1-MCM3;P1CDC47;P85MCM;PNAS146;PPP1R104 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 4176 Swiss Prot P33993 保存 Store at -20°C. Avoid freeze / thaw cycles. 蛋白分子量 45/61/81kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus 免疫原 A synthetic peptide of human MCM7 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. Public Immunogen Range 485-535/719aa 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。