靶标 ARNT 别名 ARNT;HIF-1-beta;HIF-1beta;HIF1-beta;HIF1B;HIF1BETA;TANGO;bHLHe2 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 405 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P27540 蛋白分子量 85/86/87kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus 免疫原 A synthetic peptide of human ARNT 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] Public Immunogen Range 135-185/789aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Rabbit Rat Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。