靶标 Keratocan 别名 CNA2; KERA; KERA_HUMAN; Keratan sulfate proteoglycan keratocan; Keratocan; KTN; SLRR2B. 宿主 Rabbit 稀释比例 WB 1:500-2000. ELISA 1:5000-10000. Gene ID 11081 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O60938 蛋白分子量 38kDa 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 亚细胞定位 Extracellular matrix Secreted 免疫原 KLH conjugated synthetic peptide derived from human Keratocan 亚型 IgG 纯化方法 Affinity purification 背景资料 Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan,Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened. 克隆类型 Polyclonal Antibody 交叉反应 Mouse 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。