靶标 MME 别名 CALLA;CD10;CMT2T;NEP;SCA43;SFE;MME 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 4311 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P08473 蛋白分子量 86kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cell membrane Cytoplasm 免疫原 A synthetic peptide of human MME 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008] Public Immunogen Range 700-750/750aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Rabbit Chimpanzee Rat Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。