靶标 ERCC6L 别名 PICH;RAD26L 宿主 Rabbit 稀释比例 WB 1:1000-3000. IHC 1:100-300. Gene ID 54821 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q2NKX8 蛋白分子量 141kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 Recombinant protein of human ERCC6L 亚型 IgG 纯化方法 Affinity purification 背景资料 DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin (PubMed:17218258). Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase (PubMed:17218258, PubMed:23973328). Functions as ATP-dependent DNA translocase (PubMed:23973328, PubMed:28977671). Can promote Holliday junction branch migration (in vitro) (PubMed:23973328). Public Immunogen Range 832-1250aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。