靶标 MLKL 别名 FLJ34389, MLKL 宿主 Mouse 稀释比例 WB 1:2000-10000. IHC 1:500-2000. IF 1:50-500 Gene ID 197259 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot Q8NB16 蛋白分子量 54kDa 储存液 PBS with 0.02% sodium azide,50% glycerol,pH7.3. 亚细胞定位 Cell membrane Cytoplasm 免疫原 Recombinant protein of human MLKL. 亚型 IgG1 纯化方法 Affinity purification 背景资料 Mixed lineage kinase domain like pseudokinase (MLKL), belongs to the protein kinase superfamily, has two MW of 54 and 30 kDa. MLKL plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. 66675-1-Ig antibody recognizes 54 kDa MLKL monomer, 216 kDa MLKL tetramer and a band around 45-50 kDa which are similar to papers published. (PMID: 31848291) 克隆类型 Monoclonal antibody 交叉反应 Human Mouse 应用 WB ELISA IF IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。