靶标 PLK3 别名 PLK3;CNK;FNK;PLK-3;PRK 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 1263 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9H4B4 蛋白分子量 72kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus Cytoplasm 免疫原 A synthetic peptide of human PLK3 亚型 IgG 纯化方法 Affinity purification 背景资料 The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. Public Immunogen Range 35-85/646aa 克隆类型 Polyclonal Antibody 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。