靶标 TNFRSF11B 别名 OCIF;OPG;PDB5;TR1 宿主 Rabbit 预测交叉反应 Bovine 稀释比例 WB 1:2000-5000.;IHC 1:50-200. Gene ID 4982 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O00300 蛋白分子量 46kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 Recombinant protein of human TNFRSF11B 亚型 IgG 纯化方法 Affinity purification 背景资料 Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. Public Immunogen Range 20-370aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 WB;IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。