英文名称 Anti-Neuropilin 1 Monoclonal Antibody 靶标 Neuropilin 1 别名 BDCA4, CD304, neuropilin 1, NRP, NRP1, VEGF165R 宿主 Mouse 稀释比例 WB : 1:1000-1:6000. IF : 1:50-1:500. FCM :0.2μg/Test. Gene ID 8829 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot O14786 蛋白分子量 103kDa 储存液 Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. 亚细胞定位 Cell membrane Secreted Single-pass type I membrane protein 免疫原 Recombinant protein of human Neuropilin 1 亚型 IgG1 纯化方法 Affinity purification 背景资料 Neuropilin-1 (NRP1) is a a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion. 克隆类型 Monoclonal antibody 交叉反应 Human pig 应用 WB ELISA IF FC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。