靶标 PKC Alpha 别名 AAG6, PKC A, PKC alpha, PKCA, PKCα, PRKACA, PRKCA, Protein kinase C alpha type, protein kinase C, alpha 宿主 Mouse 稀释比例 WB 1:5000-10000. IHC 1:50-500. IF 1:200-800 Gene ID 5578 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot P17252 蛋白分子量 76kDa 储存液 PBS with 0.02% sodium azide,50% glycerol,pH7.3. 亚细胞定位 Cell membrane Cytoplasm Mitochondrion membrane Nucleus Peripheral membrane protein 免疫原 Recombinant protein of human PKC Alpha. 亚型 IgG1 纯化方法 Affinity purification 背景资料 Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PRKCA is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. 克隆类型 Monoclonal antibody 交叉反应 Human Rat Mouse 应用 WB ELISA IF IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。