靶标 PLA2G4A 别名 PLA2G4A;PLA2G4;cPLA2;cPLA2-alpha 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 5321 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P47712 蛋白分子量 85kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 A synthetic peptide of human PLA2G4A 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. Public Immunogen Range 440-490/749aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Chimpanzee 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。