英文名称 Anti-FCHO2 Polyclonal Antibody 靶标 FCHO2 别名 F-BAR domain only protein 2; 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 115548 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q0JRZ9 蛋白分子量 43/85/89kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Cell membrane 免疫原 Recombinant protein of human FCHO2 亚型 IgG 纯化方法 Affinity purification 背景资料 Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor. Public Immunogen Range 1-375aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Zebrafish Orangutan Rat Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。