靶标 Casein Kinase 1 alpha 别名 CK1; CK1a; CKIa; HEL-S-77p; HLCDGP1; PRO2975 宿主 Rabbit 稀释比例 WB 1:500-2000. IHC 1:50-200. Gene ID 1452 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot P48729 蛋白分子量 35kDa 储存液 PBS with 0.02% sodium azide,50% glycerol,pH7.3. 亚细胞定位 Chromosome Cytoplasm Nucleus speckle centromere centrosome cytoskeleton kinetochore microtubule organizing center 免疫原 A synthesized peptide derived from human Casein Kinase 1 alpha 亚型 IgG 纯化方法 Affinity purification 背景资料 Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108).May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688). 克隆类型 Monoclonal antibody 交叉反应 Human Rat Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。