靶标 DCX/Doublecortin 别名 Doublecortex; DBCN; Dbct; DC; Doublin; Lis X; Lissencephalin X; Lissencephaly X linked;Lissencephaly X linked doublecortin; LISX; Neuronal migration protein doublecortin; SCLH; XLIS 宿主 Rabbit 稀释比例 WB 1:500-2000. ELISA 1:5000-10000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:50-200. Gene ID 1641 保存 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Swiss Prot O43602 蛋白分子量 49kDa 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 亚细胞定位 Cytoplasmic 免疫原 KLH conjugated synthetic peptide derived from human DCX 亚型 IgG 纯化方法 Affinity purification 背景资料 Doublecortin (DCX) is a microtubule-associated protein expressed almost exclusively in immature neurons. Neuronal precursors begin to express DCX shortly after exiting the cell cycle, and continue to express DCX for 2-3 weeks as the cells mature into neurons. Downregulation of DCX begins after 2 weeks, and occurs at the same time that these cells begin to express, a marker for mature neurons. Due to the nearly exclusive expression of DCX in developing neurons, this protein has been used increasingly as a marker for neurogenesis. Indeed, the levels of DCX expression increase in response to exercise, which occurs in parallel with increased BrdU labelling, currently a gold standard in measuring neurogenesis. 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB IF IHC-F IHC-P ELISA 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。