Solarbio K111081P Anti-DYR1A Polyclonal Antibody
- 销售价:
- ¥768.00
- 市场价:
-
¥960.00 - 编号:
- 202302241034983
- 货号:
- K111081P-50ul
-
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商品介绍
靶标
DYR1A
别名
DYRK1A;DYRK;DYRK1;HP86;MNB;MNBH;MRD7
宿主
Rabbit
稀释比例
IHC 1:100-300.
Gene ID
1859
保存
Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot
Q13627
蛋白分子量
60/66/85/86kDa
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位
Nucleus Cytoplasm
免疫原
A synthetic peptide of human DYR1A
亚型
IgG
纯化方法
Affinity purification
背景资料
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.
Public Immunogen Range
25-75/763aa
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
IHC
规格
50ul 100ul
使用前请离心。如有问题请及时联系我们。
商品参数
商品介绍 | |
---|---|
单位 | 支 |
品牌 | Solarbio |
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