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Solarbio K111081P Anti-DYR1A Polyclonal Antibody

销售价:
¥768.00
市场价:
¥960.00
编号:
202302241034983
货号:
K111081P-50ul
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产品规格:
100ul 50ul
数量:

商品介绍

靶标 DYR1A 别名 DYRK1A;DYRK;DYRK1;HP86;MNB;MNBH;MRD7 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 1859 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q13627 蛋白分子量 60/66/85/86kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus Cytoplasm 免疫原 A synthetic peptide of human DYR1A 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. Public Immunogen Range 25-75/763aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。

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品牌 Solarbio

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