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Solarbio K110816P Anti-GNAI3 Polyclonal Antibody

销售价:
¥768.00
市场价:
¥960.00
编号:
202302241034978
货号:
K110816P-50ul
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产品规格:
100ul 50ul
数量:

商品介绍

英文名称 Anti-GNAI3 Polyclonal Antibody 靶标 GNAI3 别名 G(i) alpha-3;87U6;ARCND1; 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 2773 Swiss Prot P08754 保存 Store at -20°C. Avoid freeze / thaw cycles. 蛋白分子量 41kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human GNAI3 亚型 IgG 纯化方法 Affinity purification 背景资料 Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed:8774883, PubMed:18434541, PubMed:19478087). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (PubMed:19478087). Stimulates the activity of receptor-regulated K+ channels (PubMed:2535845). The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division (PubMed:17635935). Public Immunogen Range 304-354/354 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。

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品牌 Solarbio

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