英文名称 Anti-PCBP1 Polyclonal Antibody 靶标 PCBP1 别名 PCBP1; HEL-S-85; HNRPE1; HNRPX; hnRNP-E1; hnRNP-X; poly(rC)-binding protein 1 宿主 Rabbit 稀释比例 WB 1:1000-3000. IHC 1:50-200. Gene ID 5093 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q15365 蛋白分子量 37kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 Recombinant protein of human PCBP1 亚型 IgG 纯化方法 Affinity purification 背景资料 This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. Public Immunogen Range 1-356aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Bovine Rabbit Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。