靶标 CD11b 别名 CD11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1 宿主 Rat 稀释比例 FCM:10^6cells加0.3ug Gene ID 16409 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot P05555 蛋白分子量 125kDa 储存液 PBS with 0.1% sodium azide and a stabilizer. 亚细胞定位 Cell membrane 免疫原 C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes 亚型 IgG2b 纯化方法 Affinity purification 背景资料 Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). 克隆类型 Monoclonal antibody 交叉反应 Mouse 规格 25ug 100ug 使用前请离心。如有问题请及时联系我们。