靶标 PNPLA8 别名 Calcium-independent phospholipase A2-gamma; Intracellular membrane associated calcium independent phospholipase A2 gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; IPLA2 2; iPLA2 gamma 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 50640 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9NP80 蛋白分子量 77/82/88kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human PNPLA8 亚型 IgG 纯化方法 Affinity purification 背景资料 Calcium-independent phospholipase A2, which promotes cellular membrane hydrolysis and prostaglandin production (PubMed:10744668, PubMed:15695510). Catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, phosphytidylserine and to a lower extent phosphatidylcholine (PubMed:10744668). Cleaves membrane phospholipids (PubMed:15695510). Participates in the generation of lipid second messengers through the mobilization of arachidonic acid in response to cellular stimuli. Synthesizes 2-arachidonoyl lysophosphatidylcholine, a key branch point metabolite in eicosanoid signaling (PubMed:15908428). Participates in the lipid plasticity of myocardium, plays a role in the generation of signaling metabolites and has a prominent effect on the modulaton of energy storage and utilization (PubMed:17213206). Essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition (By similarity). Public Immunogen Range 200-250/782aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。