靶标 CDH3 别名 CDH3;CDHP;HJMD;PCAD 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 1001 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P22223 蛋白分子量 87/91kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cell membrane Cytoplasm 免疫原 A synthetic peptide of human CDH3 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). Public Immunogen Range 305-355/829aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Chicken Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。