英文名称 Anti-AGO3 Polyclonal Antibody 靶标 AGO3 别名 Protein argonaute-3;Argonaute3;hAgo3;EIF2C3; 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 192669 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9H9G7 蛋白分子量 71/97kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 Recombinant protein of human AGO3 亚型 IgG 纯化方法 Affinity purification 背景资料 Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713). Public Immunogen Range 1-230aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Bovine Zebrafish Chicken Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。