靶标 REN 别名 REN;HNFJ2;renin;Renin 宿主 Rabbit 预测交叉反应 Chimpanzee;Monkey 稀释比例 IHC 1:25-100. Gene ID 5972 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P00797 蛋白分子量 45kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Secreted 免疫原 A synthetic peptide of human REN 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. Public Immunogen Range 290-340/406aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。