靶标 PARP1 (Cleaved-Gly215) 别名 ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;PARP1;Cleaved PARP;PARP1 宿主 Rabbit 稀释比例 WB 1:1000-3000. IHC 1:50-200. Gene ID 142 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P09874 蛋白分子量 113kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus Cytoplasm 免疫原 A synthetic peptide of human PARP1 (Cleaved-Gly215) 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008] Public Immunogen Range 180-230/1014aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。