靶标 ADGRE5(Cleaved-Leu530) 别名 ADGRE5;CD97;TM7LN1 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 976 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P48960 蛋白分子量 82/87/92kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Secreted Cell membrane 免疫原 A synthetic peptide of human ADGRE5(Cleaved-Leu530) 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. Public Immunogen Range 495-545/835aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Cow Dog 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。