英文名称 Anti-NDFIP1 Polyclonal Antibody 靶标 NDFIP1 别名 N4WBP5, NDFIP1, PSEC0223 宿主 Rabbit 稀释比例 WB 1:200-1000.IF 1:20-200.IP 0.5-4.0 ug for IP and 1:200-1:1000 for WB. Gene ID 80762 保存 Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. Swiss Prot Q9BT67 蛋白分子量 25 kDa 储存液 PBS with 0.02% sodium azide and 50% glycerol pH 7.3. 亚细胞定位 Secreted 免疫原 Fusion protein of human NDFIP1 亚型 IgG 纯化方法 Affinity purification 背景资料 Ndfip1 is an adaptor protein for the Nedd4 family of ubiquitin ligases and has been found to be upregulated in neurons after brain injury, including head trauma, stroke and metal toxicity. Recent studies confirmed the role of Ndfip1 as a regulator of iron metabolism and pointed out that Ndfip1 was involved in iron homeostasis by regulating the degradation of iron importer divalent metal transporter 1. Ndfip1 is a transmembrane protein that is localized to the Golgi and post-Golgi vesicles such as endosomes. It is an adaptor protein that recruits E3 ligases to ubiquitinate target proteins. It is ubiquitously expressed and contains 2 PY motifs, which interact with several Nedd4 family E3s to degradate proteins. 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB ELISA IP IF 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。