靶标 NFIL3 别名 E4BP4;IL3BP1;NF-IL3A;NFIL3A 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 4783 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q16649 蛋白分子量 51kd 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus 免疫原 A synthetic peptide of human NFIL3 亚型 IgG 纯化方法 Affinity purification 背景资料 Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death (By similarity). Represses the transcription of CYP2A5 (By similarity). Positively regulates the expression and activity of CES2 by antagonizing the repressive action of NR1D1 on CES2 (By similarity). Public Immunogen Range 190-240/462aa 克隆类型 Polyclonal Antibody 交叉反应 Human Predicted:Cow 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。