英文名称 Anti-MOV10L1 Polyclonal Antibody 靶标 MOV10L1 别名 CHAMP;DJ402G11.8;DKFZp434B0717 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 54456 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9BXT6 蛋白分子量 14/38/130/135kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human MOV10L1 亚型 IgG 纯化方法 Affinity purification 背景资料 ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins. Public Immunogen Range 95-145/1211aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。