英文名称 Anti-BCAP31 Polyclonal Antibody 靶标 BCAP31 别名 6C6-AG;BAP31;CDM;DDCH;DXS1357E; 宿主 Rabbit 预测交叉反应 Chimpanzee 稀释比例 IHC 1:50-200. Gene ID 10134 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P51572 蛋白分子量 28/35kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human BCAP31 亚型 IgG 纯化方法 Affinity purification 背景资料 Functions as a chaperone protein (PubMed:9396746, PubMed:18287538). Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:9396746, PubMed:18287538). Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:9396746, PubMed:18287538). Also serves as a cargo receptor for the export of transmembrane proteins (By similarity). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed:31206022). In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed:31206022). May be involved in CASP8-mediated apoptosis (PubMed:10958671). Public Immunogen Range 55-105/246aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。