靶标 PPP1R16B 别名 ANKRD4;KIAA0823;TIMAP 宿主 Rabbit 预测交叉反应 Cow;Xenopus tropicalis 稀释比例 WB 1:1000-3000. Gene ID 26051 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q96T49 蛋白分子量 59/64kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Nucleus 免疫原 A synthetic peptide of human PPP1R16B 亚型 IgG 纯化方法 Affinity purification 背景资料 Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function (PubMed:18586956). Involved in the regulation of the PI3K/AKT signaling pathway, angiogenesis and endothelial cell proliferation (PubMed:25007873). Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity (By similarity). Protects the endothelial barrier from lipopolysaccharide (LPS)-induced vascular leakage (By similarity). Involved in the regulation of endothelial cell filopodia extension (By similarity). May be a downstream target for TGF-beta1 signaling cascade in endothelial cells (PubMed:16263087, PubMed:18586956). Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation (PubMed:18586956). Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1 (PubMed:16263087). Involved in the dephosphorylation of EEF1A1 (PubMed:26497934). Public Immunogen Range 15-65/567aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。