靶标 CCP110 别名 110 kDa centrosomal protein;CCP110;Centriolar coiled coil protein 110kDa;Centrosomal protein 110 kDa;Centrosomal protein CP110;Centrosomal protein of 110 kDa;Cep110;CP110 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 9738 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O43303 蛋白分子量 113kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human CCP110 亚型 IgG 纯化方法 Affinity purification 背景资料 Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). Public Immunogen Range 135-185/1012aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。