英文名称 Anti-INS Polyclonal Antibody 靶标 INS 别名 IDDM;IDDM1;IDDM2;ILPR;ins;INS_HUMAN;Insulin A chain;Insulin B chain;IRDN;MODY10;Preproinsulin;Proinsulin;Proinsulin precursor; 宿主 Rabbit 预测交叉反应 Chimpanzee;Monkey;Opossums;Camel;Goat;Horse;Sheep;Cow;Pig;Hamster;Rabbit;Cat;Dog;Duck;Turtle;Bird;Chicken;Fish;Xenopus laevis 稀释比例 IHC 1:50-200. Gene ID 3630 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P01308 蛋白分子量 12/22kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Secreted 免疫原 A synthetic peptide of human INS 亚型 IgG 纯化方法 Affinity purification 背景资料 After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] Public Immunogen Range 15-65/110aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。