靶标 KISS1R 别名 AXOR12;CPPB1;GPR54;HH8;HOT7T175;KISS-1R;AXOR 12;AXOR12;G protein coupled receptor 54;G-protein coupled receptor 54;G-protein coupled receptor OT7T175;GPCR 54;GPCR54;GPR 54;GPR54;hOT7T175;Hypogonadotropin 1;Hypogonadotropin-1;Hypogonadotropin1;KISS 1 receptor;KISS 1R;KiSS-1 receptor;KiSS-1R;KISS1 receptor;Kiss1r;Kisspeptins receptor;KISSR_HUMAN;Metastin receptor;OT7T175 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 84634 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q969F8 蛋白分子量 43kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cell membrane Cytoplasm 免疫原 A synthetic peptide of human KISS1R 亚型 IgG 纯化方法 Affinity purification 背景资料 Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins. Public Immunogen Range 255-305/398aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。