靶标 BMPR2 别名 BMP type II receptor;BMP type-2 receptor;BMPR 2;BMPR 3;BMPR II;BMPR-2;BMPR-II;Bmpr2;BMPR2_HUMAN;BMPR3;BMPRII;BMR 2;BMR2;Bone morphogenetic protein receptor type 2;Bone morphogenetic protein receptor type II;Bone morphogenetic protein receptor type-2;Bone morphogenic protein receptor type II serine threonine kinase;BRK 3;BRK3;PPH 1;PPH1;Serine threonine kinase type II activin receptor like kinase;T ALK;TALK;Type II activin receptor like kinase 宿主 Rabbit 稀释比例 WB 1:1000-3000.;IHC 1:100-300. Gene ID 659 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q13873 蛋白分子量 60/115kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cell membrane Secreted Nucleus 免疫原 Recombinant protein of human BMPR2 亚型 IgG 纯化方法 Affinity purification 背景资料 On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. Public Immunogen Range 600-950aa 克隆类型 Polyclonal Antibody 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。