英文名称 Anti-BIN1 Polyclonal Antibody 靶标 BIN1 别名 AMPH 2;AMPH2;Amphiphysin 2;Amphiphysin II;Amphiphysin like protein;amphiphysin-like;Amphiphysin-like protein;AMPHL;Bin1;BIN1_HUMAN;Box Dependant MYC Interacting Protein 1;Box-dependent myc-interacting protein 1;Bridging integrator 1;DKFZp547F068;MGC10367;MGC105358;Myc box dependent interacting protein 1;Myc box-dependent-interacting protein 1;SH3P9 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 274 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O00499 蛋白分子量 46/47/48/50/52/53/55/56/60/65kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human BIN1 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. Public Immunogen Range 55-105/593aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。