靶标 MYO10 别名 myosin X;Unconventional myosin-X;Unconventional myosin-10;KIAA0799 宿主 Rabbit 预测交叉反应 Bovine 稀释比例 WB 1:1000-3000.;IHC 1:100-300. Gene ID 4651 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9HD67 蛋白分子量 11/164/237kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Nucleus Cell membrane 免疫原 Recombinant protein of human MYO10 亚型 IgG 纯化方法 Affinity purification 背景资料 Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts. Public Immunogen Range 1-98aa 克隆类型 Polyclonal Antibody 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。