英文名称 Anti-Phospho-P38 MAPK(Thr180+Tyr182) Polyclonal Antibody 靶标 Phospho-P38 MAPK(Thr180+Tyr182) 别名 P38 MAPK(Phospho-Thr180); phospho-MAPK14(Thr180/Tyr182); MAPK14(phospho Thr180/Tyr182); CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX interacting protein 2; MAX-interacting protein 2; Mitogen Activated Protein Kinase 14; Mitogen activated protein kinase p38 alpha; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; MK14_HUMAN; Mxi 2; Mxi2; p38 ALPHA; p38; p38 MAP kinase; p38 MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A. 宿主 Rabbit 预测交叉反应 Dog;Rabbit 稀释比例 WB 1:500-2000;IHC 1:100-500;FCM=1μg/Test;IF 1:100-500. Gene ID 1432 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q16539 蛋白分子量 42kDa 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 亚细胞定位 Cytoplasm Cell membrane 免疫原 A synthetic peptide of human p38 MAPK around the phosphorylation site of Thr180/Tyr182: M(p-T)G(p-Y)VA 亚型 IgG 纯化方法 Affinity purification 背景资料 The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases(MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 WB;IHC;IF;FCM 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。